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The prolific pipeline is about genome annotation and metabolic pathway reconstruction. From .fasta genomes, it enables to find if strains of bacteria are theorically able to produce metabolites

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Prolipipe : large-scale assessment of metabolic profiles on bacteria focusing on specific pathways.

Workflow to reconstruct multiple metabolic graphs and assess capacity to synthesize specific compounds.

This workflow is licensed under the GNU GPL-3.0-or-later, see the LICENSE file for details.

Prolipipe relies on "MeReco" package

These python packages are needed :

If you have installed all the dependencies listed here and on MeReco's page, you can just install prolipipe with:

pip install mereco
pip install prolipipe
prolipipe.py [-h] -i INPUT -o OUTPUT --tax TAXFILE --padmet_ref PATH_TO_PADMET_REF --ptsc PTSC --ptsi PTSI --pwy PWY_FOLD --strain STRAIN
                                    [--annot ANNOT] [--egg_path EGG_PATH] [--bak_path BAK_PATH] [-c CPUS] [-a] [-k] [-q]

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The prolific pipeline is about genome annotation and metabolic pathway reconstruction. From .fasta genomes, it enables to find if strains of bacteria are theorically able to produce metabolites

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